Search results for "model [interaction]"
showing 10 items of 1495 documents
Existence of a unique solution for a third-order boundary value problem with nonlocal conditions of integral type
2021
The existence of a unique solution for a third-order boundary value problem with integral condition is proved in several ways. The main tools in the proofs are the Banach fixed point theorem and the Rus’s fixed point theorem. To compare the applicability of the obtained results, some examples are considered.
Longevity: epigenetic and biomolecular aspects
2015
AbstractMany aging theories and their related molecular mechanisms have been proposed. Simple model organisms such as yeasts, worms, fruit flies and others have massively contributed to their clarification, and many genes and pathways have been associated with longevity regulation. Among them, insulin/IGF-1 plays a key and evolutionary conserved role. Interestingly, dietary interventions can modulate this pathway. Calorie restriction (CR), intermittent fasting, and protein and amino acid restriction prolong the lifespan of mammals by IGF-1 regulation. However, some recent findings support the hypothesis that the long-term effects of diet also involve epigenetic mechanisms. In this review, w…
Quality System for Production Software as Tool for Monitoring and Improving Organization KPIs
2013
In this paper we propose a solution as support for quality systems for production software. The motivation behind this study was to reduce that cost in the production area caused by gaps in the quality of the production software. Our proposal: QSPS (Quality System for Production Software) is offering support in the "vulnerable points" of these quality systems which usually generate nonconformities and have proved to be difficult or impossible to control. QSPS is a method in seven steps or modules that integrates also software tools, templates, checklists, evaluating tools elaborated complying to products, process and system quality standards. If other analyzed methods like: Scrum, XP, Fuzzy…
A soft-quadrumer model for diblock copolymers
2010
We present a new soft-particle type model for diblock copolymers and compare its phase diagram to experimental data as well as to results of other models. To determine the phase diagram we suggest studying geometrical characteristics of the mesophases. Diblock copolymer mesophases differ by the number and geometrical form of clusters of the two components formed in the mesophase. The form of these clusters can be characterized by values of the principle components of their gyration tensor and shape invariants determined from them. Alternatively, it has been suggested to use Minkowski functionals to characterize the global morphology of the different mesophases. We will also discuss the prac…
ChemInform Abstract: Discrimination and Molecular Design of New Theoretical Hypolipaemic Agents Using the Molecular Connectivity Functions.
2010
The molecular topology model and discriminant analysis have been applied to the prediction and QSAR interpretation of some pharmacological properties of hypolipaemic drugs using multivariable regre...
Discrimination and Molecular Design of New Theoretical Hypolipaemic Agents Using the Molecular Connectivity Functions
2000
The molecular topology model and discriminant analysis have been applied to the prediction and QSAR interpretation of some pharmacological properties of hypolipaemic drugs using multivariable regression equations with their statistical parameters. Regression analysis showed that the molecular topology model predicts these properties. The corresponding stability (cross-validation) studies done on the selected prediction models confirmed the goodness of the fits. The method used for hypolipaemic activity selection was a linear discriminant analysis (LDA). We make use of the pharmacological distribution diagrams (PDDs) as a visualizing technique for the identification and design of new hypolip…
Toward the Physical Interpretation of Inductive and Resonance Substituent Effects and Reexamination Based on Quantum Chemical Modeling
2017
An application of a charge of the substituent active region concept to 1-Y,4-X-disubstituted derivatives of bicyclo[2.2.2]octane (BCO) [where Y = NO2, COOH, OH, and NH2 and X = NMe2, NH2, OH, OMe, Me, H, F, Cl, CF3, CN, CHO, COMe, CONH2, COOH, NO2, and NO] provides a quantitative information on the inductive component of the substituent effect (SE). It is shown that the effect is highly additive but dependent on the kind of substituents. An application of the SE stabilization energy characteristics to 1,4-disubstituted derivatives of BCO and benzene allows the definition of inductive and resonance contributions to the overall SE. Good agreements with empirical approaches are found. All calc…
Quark Structure of the X (4500), X (4700) and χc(4P,5P) States
2021
We study some of the main properties (masses and open-flavor strong decay widths) of 4P and 5P charmonia. While there are two candidates for the χc0(4P,5P) states, the X(4500) and X(4700), the properties of the other members of the χc(4P,5P) multiplets are still completely unknown. With this in mind, we start to explore the charmonium interpretation for these mesons. Our second goal is to investigate if the apparent mismatch between the Quark Model (QM) predictions for χc0(4P,5P) states and the properties of the X(4500) and X(4700) mesons can be overcome by introducing threshold corrections in the QM formalism. According to our coupled-channel model results for the threshold mass shifts, th…
Predictions from warped flavor dynamics based on the T′ family group
2020
We propose a realistic theory of fermion masses and mixings using a five-dimensional warped scenario where all fermions propagate in the bulk and the Higgs field is localized on the IR brane. The assumed $T'$ flavor symmetry is broken on the branes by flavon fields, providing a consistent scenario where fermion mass hierarchies arise from adequate choices of the bulk mass parameters, while quark and lepton mixing angles are restricted by the family symmetry. Neutrino mass splittings, mixing parameters and the Dirac CP phase all arise from the type-I seesaw mechanism and are tightly correlated, leading to predictions for the neutrino oscillation parameters, as well as expected \znbb decay ra…
Search for Charged Higgs Bosons Decaying into Top and Bottom Quarks in pp Collisions
2009
Made available in DSpace on 2022-04-28T20:54:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-05-14 We describe a search for production of a charged Higgs boson, qq̄′→H+, reconstructed in the tb̄ final state in the mass range 180≤MH+≤300GeV. The search was undertaken at the Fermilab Tevatron collider with a center-of-mass energy s=1.96TeV and uses 0.9fb-1 of data collected with the D0 detector. We find no evidence for charged Higgs boson production and set upper limits on the production cross section in the types I, II, and III two-Higgs-doublet models (2HDMs). An excluded region in the (MH+, tanβ) plane for type I 2HDM is presented. © 2009 The American Physical Society. Universida…